DQB1 Rabbit Polyclonal Antibody, 50ul Filtration Its function in proximal tubular

Its function in proximal tubular epithelial cells and other cell types is less clear

Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes

In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5

and Rab (see MIM 179508) families

and a C-terminal cysteine knot

DQB1 Rabbit Polyclonal Antibody, 50ul Filtration Its function in proximal tubularHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB) both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The beta chain is approximately 26 28 kDa and it contains