53BP1 Polyclonal Antibody, 50ul[BT-AP00042] In vitro Assessment cow and mouse

cow and mouse

The neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase| which produces superoxide anion

Also functions as a receptor for various alkaloids and psychoactive substances

tissue specificity:B-cell specific

This kinase contains a SH3 domain and a leucine zipper-basic motif

53BP1 Polyclonal Antibody, 50ul[BT-AP00042] In vitro Assessment cow and mouseThe p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA binding domain of wild type p53, but do not bind mutant p53. The central DNA binding domain of p53 is required for site specific DNA binding and is frequently mutated in malignant tumors. Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation. Site specific binding also suggests that 53BP1 and 53BP2 are