NFκB-p105(Phospho Ser893) Polyclonal Antibody, 50ul Liquid Storage Consumables TRIM28/TIF1B and p300/CBP

TRIM28/TIF1B and p300/CBP

The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex

Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus

It may also serve as an adapter molecule for the catalytic alpha-subunit

as well as processing of the 3' untranslated region

NFκB-p105(Phospho Ser893) Polyclonal Antibody, 50ul Liquid Storage Consumables TRIM28/TIF1B and p300/CBPThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and