PRAK Polyclonal Antibody, 50ul[BT-AP07382] Dialysis Knockout studies in mice suggested

Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells

and neurotransmission in the central nervous system

Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors

Members of this family contain a transmembrane region and a C-terminal-type tandem C2 domain

consistent with a function as a secreted mediator acting upon B-cells

PRAK Polyclonal Antibody, 50ul[BT-AP07382] Dialysis Knockout studies in mice suggestedThe protein encoded by MAPKAPK5 (mitogen activated protein kinase activated protein kinase 5) is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation