ARHGEF9 Polyclonal Antibody, 50ul DNA Fragments Contains 1 Myb-like domain

Contains 1 Myb-like domain

An important paralog of this gene is GPRIN3

Contains 1 SEC7 domain

SCN9A (sodium voltage-gated channel alpha subunit 9) encodes a voltage-gated sodium channel which plays a significant role in nociception signaling

The DHR-2 domain is necessary for the GEF activity

ARHGEF9 Polyclonal Antibody, 50ul DNA Fragments Contains 1 Myb-like domainThe Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho like GTPase that switches between the active (GTP bound) state and inactive (GDP bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.