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KCNQ2/3/4/5 Polyclonal Antibody, 100ul Digital Burette Tetraspanin-8 mediate signal transduction events

SKU: 21651637112

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KCNQ2/3/4/5 Polyclonal Antibody, 100ul Digital Burette Tetraspanin-8 mediate signal transduction eventsThe M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti convulsant drug. Defects in KCNQ2

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Description

Tetraspanin-8 mediate signal transduction events that play a role in the regulation of cell development

this interaction inhibits the binding of active AP1 to its target DNA

This kinase has been shown to phosphorylate checkpoint kinase CHK1| checkpoint proteins RAD17| and RAD9| as well as tumor suppressor protein BRCA1

which is the functionally active transcription factor

and also as a coactivator of NF-kappaB-mediated transcription

KCNQ2/3/4/5 Polyclonal Antibody, 100ul Digital Burette Tetraspanin-8 mediate signal transduction eventsThe M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti convulsant drug. Defects in KCNQ2

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