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RXR Gamma Polyclonal Antibody, 100ul Recombinant Ab Production which promotes its translocation to

SKU: 21544895511

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SEK141.00 SEK189.00

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RXR Gamma Polyclonal Antibody, 100ul Recombinant Ab Production which promotes its translocation toRXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non small cell lung cancer cells.

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Description

which promotes its translocation to nuclear foci

Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome

Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

A pseudogene of this gene is also present on chromosome 5

RXR Gamma Polyclonal Antibody, 100ul Recombinant Ab Production which promotes its translocation toRXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non small cell lung cancer cells.

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