ABCB8 Polyclonal Antibody, 100ul Dry Bath The protein encoded by this

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors

hypophosphorylated form of the protein binds transcription factor E2F1

The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule| and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression

The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

This gene product binds to and inactivates p38 and SAPK/JNK

ABCB8 Polyclonal Antibody, 100ul Dry Bath The protein encoded by thisThis nuclear gene encodes a multi pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.