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Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma It possesses at least two

SKU: 2153526028

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Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma It possesses at least twoThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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Description

It possesses at least two conserved domains that could be important for its function

Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD)

Catalytic activity:Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus| at 775-Gly-|-Ile-776 in the alpha-1(I) chain

Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization

The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases

Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma It possesses at least twoThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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