Human Thioredoxin-interacting Protein, TXNIP ELISA Kit , 96T Adenovirus Packaging When translation ends upstream from

When translation ends upstream from the last exon-exon junction| this triggers NMD to degrade mRNAs containing premature stop codons

Acts as a ligand for C-C chemokine receptor CCR2 (By similarity)

have been localized to distinct regions of the nucleus

Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2

The G-protein signaling modulator 1 contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half

Human Thioredoxin-interacting Protein, TXNIP ELISA Kit , 96T Adenovirus Packaging When translation ends upstream fromMay act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5 induced suppression of CDKN1B stability, blocking the COPS5 mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over expression will induce G0 G1