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Rb Polyclonal Antibody, 20ul[BT-AP07687] Vortex Mixer Misshapen-like kinase 1 is structurally

SKU: 21467268121

4.1
SEK111.00 SEK161.00

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Rb Polyclonal Antibody, 20ul[BT-AP07687] Vortex Mixer Misshapen-like kinase 1 is structurallyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Misshapen-like kinase 1 is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family

GTP-bound G alpha subunits

No adsorption of cytokines or growth factors

Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes

Potassium voltage-gated channel subfamily KQT member 4 encoded by KCNQ4 forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability

Rb Polyclonal Antibody, 20ul[BT-AP07687] Vortex Mixer Misshapen-like kinase 1 is structurallyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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