p57(Phospho Thr310) Polyclonal Antibody, 100ul Aspirating Pipets This gene encodes a preproprotein

This gene encodes a preproprotein that is proteolytically processed to generate two protein products| megakaryocyte potentiating factor and mesothelin

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis

The WW domains are essential for localization to nuclear speckles

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In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

p57(Phospho Thr310) Polyclonal Antibody, 100ul Aspirating Pipets This gene encodes a preproproteinThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.