PRK2 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos The protein (toll like receptor

The protein (toll like receptor 4) encoded by TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity

The protein encoded by ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2)may form complex with G proteins and stimulate rho-dependent signals

|subcellular location:Translocates to mitochondria as an integral membrane protein

Alternative splicing of KRT13 results in multiple transcript variants

multiple phosphorylation sites

PRK2 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos The protein (toll like receptorCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,domain: The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation: Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr 816 (activation loop of the kinase domain) and Thr 958 (turn motif), need to be phosphorylated for its full activation.,function: Exhibits a preference for