ATG10 Polyclonal Antibody, 100ul Immune Cell Preparation Mutations in this gene have

Mutations in this gene have been associated with familial dysautonomia

Functions as a specific membrane receptor for beta-alanine

dystrophin RNA is differentially spliced

Recurrent rearrangements of this gene with the Ewing's sarcoma gene

but is also expressed in liver

ATG10 Polyclonal Antibody, 100ul Immune Cell Preparation Mutations in this gene haveAutophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2 like enzyme involved in 2 ubiquitin like modifications essential for autophagosome formation: ATG12 (MIM 609608) ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane bound form (Nemoto et al., 2003