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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression it has been demonstrated that

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression it has been demonstrated thatThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

it has been demonstrated that the protein actually has protein disulfide isomerase activity

This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

Several alternatively spliced transcript variants have been described for this gene

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors

The re-sealable bag keeps them organized and ready for your daring experiments

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression it has been demonstrated thatThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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