Mouse DNA Topoisomerase 1, TOP1 ELISA Kit, 96T Enzymes This form acts to modulate

This form acts to modulate the activity of the m

have an additional cyclin binding domain

Binds to a consensus sequence in gene promoters (By similarity)

The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation

The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition| phosphoinositide degeneration| and potassium channel mediation

Mouse DNA Topoisomerase 1, TOP1 ELISA Kit, 96T Enzymes This form acts to modulateReleases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA (3' phosphotyrosyl) enzyme intermediate and the expulsion of a 5' OH