UBE2K Polyclonal Antibody, 20ul Subcellular Fractions Alternatively spliced transcript variants which

Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene

This gene lies in a region of the X chromosome which has been associated with mental retardation

|induction:Regulated by cellular iron levels through binding of the iron regulatory proteins| IRP1 and IRP2| to iron-responsive elements in the 3'-UTR

This gene encodes a member of the sodium-hydrogen exchanger (NHE) protein family

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UBE2K Polyclonal Antibody, 20ul Subcellular Fractions Alternatively spliced transcript variants whichThe protein encoded by this gene belongs to the ubiquitin conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains