TRPM8 Polyclonal Antibody, 50ul ADME Members of the inhibitor of

Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains

The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule

as a sensor for oxidative stress

with no obvious relationship to other transposases

Expression of this receptor is found in vascular endothelial cells

TRPM8 Polyclonal Antibody, 50ul ADME Members of the inhibitor ofReceptor activated non selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage dependent gating. Activated upon