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Sequence variations in this gene may also be be associated with psychiatric disorders

Knockout studies of the mouse homolog suggest RAD50 is essential for cell growth and viability

Expression of this gene has been found to be upregulated in small cell lung cancers

which suggests its involvement in a regulated signaling process

MBP Monoclonal Antibody, 100ul Cryogenic Vials and push the boundaries withThis gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.