Bag-4 Polyclonal Antibody, 50ul Liquid Storage Consumables Centromere and kinetochore proteins play

Centromere and kinetochore proteins play a critical role in centromere structure

Alternatively spliced transcript variants encoding different isoforms have been found for SMARCC2

Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes

Chromosomal translocations involving CREBBP have been associated with acute myeloid leukemia

This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling| resulting in its dissociation from eIF4E and activation of mRNA translation

Bag-4 Polyclonal Antibody, 50ul Liquid Storage Consumables Centromere and kinetochore proteins playThe protein encoded by BAG4 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C terminus, which could bind and inhibit the chaperone activity