Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation Retention of resident soluble proteins

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi

Mutations in this gene are associated with defects and cancers of the immune system

This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation

The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1

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Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation Retention of resident soluble proteinsThis gene encodes a protein that regulates autophagy a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes including tumorigenesis neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.