TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in this gene have

Mutations in this gene have been associated with hereditary hemochromatosis type III

The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form

The nuclear transport factor 2 is required for nuclear import of the small Ras-like GTPase

The protein encoded by TNFRSF1A (TNF receptor superfamily member 1A) is a member of the TNF-receptor superfamily

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells

TLE2 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in this gene haveTransducin like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD repeats implicated in protein protein interaction. TLEs are transcriptional co repressors that bind to many transcription factors such as LEF1, Runx1, Oct 1, hepatocyte nuclear factor 3 as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as