PIAS 3 Polyclonal Antibody, 20ul Peptide Library Promotes integrin alpha-5/beta-1 and fibronectin

Promotes integrin alpha-5/beta-1 and fibronectin (FN) matrix assembly in breast cancer cells

The promoter polymorphism of IL12B has been reported to be associated with the severity of atopic and non-atopic asthma in children

It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells

Several pseudogenes of EIF4E are found on other chromosomes

Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency

PIAS 3 Polyclonal Antibody, 20ul Peptide Library Promotes integrin alpha-5/beta-1 and fibronectinPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.