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Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 50ul Insect Expression 59 kDa and 66 kDa

SKU: 16489921825

4.3
SEK162.00 SEK197.00

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Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 50ul Insect Expression 59 kDa and 66 kDaThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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Description

59 kDa and 66 kDa

and in T cell and B cell migration to secondary lymphoid organs

May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments

SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions

where it converts cholesteryl esters to free cholesterol for steroid hormone production

Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 50ul Insect Expression 59 kDa and 66 kDaThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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