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p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture The protein associates with several

SKU: 16421520266

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p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture The protein associates with severalTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway

including the neurotransmitters dopamine

IL26 (interleukin 26) was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells

An important paralog of this gene is AREL1

It was identified as a gene induced during terminal differentiation in melanoma cells

p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture The protein associates with severalTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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