IKK gamma(Phospho Ser376) Polyclonal Antibody, 50ul Subcellular Fractions While adducins alpha and gamma

While adducins alpha and gamma are ubiquitously expressed

transducin beta like 2 is possibly involved in some intracellular signaling pathway

Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome

or by factor VIIa (in the extrinsic pathway)

and participate in linking cadherins to intermediate filaments in the cytoskeleton

IKK gamma(Phospho Ser376) Polyclonal Antibody, 50ul Subcellular Fractions While adducins alpha and gammaThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.