HEM1 Rabbit Polyclonal Antibody, 50ul Glassware Sets Mutations in this gene can

Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease

This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity)

Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death

Interacts with RNF138/NARF and TCF7L2/TCF4

According to their substrate specificity

HEM1 Rabbit Polyclonal Antibody, 50ul Glassware Sets Mutations in this gene canThis gene encodes the mitochondrial enzyme which is catalyzes the rate limiting step in heme (iron protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down regulate the mature enzyme in mitochondria while low heme levels up regulate. A pseudogene of