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SMAD7 Polyclonal Antibody, 50ul Peptide Library These read-through transcripts are ubiquitously

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SMAD7 Polyclonal Antibody, 50ul Peptide Library These read-through transcripts are ubiquitouslyThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation

the transiently superficial layer that envelopes the developing epidermis

and murine studies suggest a role in tumor-associated tissue remodeling

The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral

The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development

SMAD7 Polyclonal Antibody, 50ul Peptide Library These read-through transcripts are ubiquitouslyThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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