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Collagen XI alpha 1 Polyclonal Antibody, 100ul Cryogenic Vials Also its presence in plasma

SKU: 14720917451

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Collagen XI alpha 1 Polyclonal Antibody, 100ul Cryogenic Vials Also its presence in plasmaThis gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants

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Description

Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis

Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene

2000 [PubMed 10799485])

probably through an TIR-TIR domain interaction with TLR4

and prescription drugs

Collagen XI alpha 1 Polyclonal Antibody, 100ul Cryogenic Vials Also its presence in plasmaThis gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants

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