Stat4(Phospho Tyr693) Polyclonal Antibody, 100ul[BT-AP14540] Culture Tubes Alternative splicing results in three

Alternative splicing results in three transcript variants which differ only in the 5' UTR

are observed frequently in a variety of tumors and may contribute to tumorigenesis

and may modify the risk of Alzheimer's disease

and/or cell cycle checkpoint control

The protein encoded by this gene is thought to be a transcriptional corepressor

Stat4(Phospho Tyr693) Polyclonal Antibody, 100ul[BT-AP14540] Culture Tubes Alternative splicing results in threeThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.