Phospho-ATRIP (S224) Polyclonal Antibody, 100ul Hepatocytes there are multiple processed pseudogenes

there are multiple processed pseudogenes of this gene dispersed through the genome

It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system

Expressed in fetal liver

This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm

suggesting a potential role in several neuropsychiatric diseases

Phospho-ATRIP (S224) Polyclonal Antibody, 100ul Hepatocytes there are multiple processed pseudogenesATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.