SMAL1 Rabbit Polyclonal Antibody, 50ul Drying & Desiccation Mutations in this gene cause

Mutations in this gene cause Darier-White disease

Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells

Members of this family contain a phox (PX) domain| which is a phosphoinositide binding domain| and are involved in intracellular trafficking

Necessary for scanning and involved in initiation site selection

resulting in downregulation of their active form

SMAL1 Rabbit Polyclonal Antibody, 50ul Drying & Desiccation Mutations in this gene causeThe protein encoded by this gene is a member of the SWI SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD) an autosomal recessive