PARP-1 Polyclonal Antibody, 50ul[BT-AP12793] Electrophoresis & Labeling This gene encodes a secreted

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

2001 [PubMed 11689425])

and progressive pulmonary fibrosis

Interacts with ATAD2 and this interaction is enhanced by estradiol

PARP-1 Polyclonal Antibody, 50ul[BT-AP12793] Electrophoresis & Labeling This gene encodes a secretedThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be