NFATc4(Phospho Ser168/S170) Polyclonal Antibody, 50ul Culture Media CRK encodes a member of

CRK encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins

The protein encoded by this gene is overexpressed in chronic lymphocytic leukemia (CLL) and serves as a good prognostic marker for the disease

GO annotations related to this gene include G-protein coupled receptor activity and trimethylamine receptor activity

This gene is classified as a pseudogene because a splice donor in the 3' UTR has changed compared to other family members| rendering the transcript a candidate for nonsense-mediated mRNA decay (NMD)

and trichothiodystrophy

NFATc4(Phospho Ser168/S170) Polyclonal Antibody, 50ul Culture Media CRK encodes a member ofThis gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin dependent phosphatase calcineurin. The encoded protein plays a