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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges or alternatively

SKU: 1309143390

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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges or alternativelyATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

or alternatively

This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction

hepatitis C virus (HCV)

This protein acts a potent mitogenic factor that plays an important role in the growth

In the absence of ligand

Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges or alternativelyATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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