ACTR-IC Polyclonal Antibody, 100ul Deep Well Plates and that binding is enhanced
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ACTR-IC Polyclonal Antibody, 100ul Deep Well Plates and that binding is enhancedACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).
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