Rat Parvalbumin Alpha, PVA1B ELISA Kit, 96T Rotator During interkinetic nuclear migration (INM)

During interkinetic nuclear migration (INM) at G2 phase and nuclear migration in neural progenitors its LINC complex association with SUN1/2 and probable association with cytoplasmic dynein-dynactin motor complexes functions to pull the nucleus toward the centrosome

PubMed: 16260596

which is thought to mimic the topology of DNA as it enters or exits the nucleosome

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

Mutations in this gene cause Joubert syndrome

Rat Parvalbumin Alpha, PVA1B ELISA Kit, 96T Rotator During interkinetic nuclear migration (INM)