Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Polyglutamine repeat expansion in the

Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy)

although the full-length nature of only two has been determined

Localizes to centrosomes

The encoded protein plays a role in cell-cycle progression and spindle organization

The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome

Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Polyglutamine repeat expansion in theHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.