IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation It encodes the alpha subunit

It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes

Transcription of this gene is highly inducible in response to many cytokines and hormones

isolated 8

also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia

DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region

IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation It encodes the alpha subunitThis gene encodes a member of the p47 immunity related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.