FTO Polyclonal Antibody, 20ul ADME Dok-5 is a tyrosine kinase

Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK)

The associated complexes play opposing roles

The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles

and even create new genes and organisms

This protein also interacts with the tumor suppressor P53 after exposure to cell stress

FTO Polyclonal Antibody, 20ul ADME Dok-5 is a tyrosine kinaseFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.