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GLRX1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Aberrant expression of this gene

SKU: 11789245083

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SEK185.00 SEK208.00

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GLRX1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Aberrant expression of this geneThis gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S glutathionylation status of signalling mediators. It is involved in beta amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced

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Description

Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types

The protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes

GO annotations related to this gene include calcium ion binding

Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA)

The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets

GLRX1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Aberrant expression of this geneThis gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S glutathionylation status of signalling mediators. It is involved in beta amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced

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