MARK1/2/3/4 Polyclonal Antibody, 50ul[BT-AP05227] Endonucleases & Exonucleases The intron 11 of the

The intron 11 of the NCL gene encodes a small nucleolar RNA

Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS| also known as Gracile Bone Dysplasia)| both characterized by short stature| hypoparathyroidism| bone development abnormalities| and hypocalcemia

The protein consists of an amino-terminal 7S domain

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a nucleoside diphosphate kinase involved in organogenesis and differentiation

MARK1/2/3/4 Polyclonal Antibody, 50ul[BT-AP05227] Endonucleases & Exonucleases The intron 11 of theMARK1 is a Protein Coding gene. Serine threonine protein kinase MARK1 involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT TAU. Involved in cell polarity by phosphorylating the microtubule associated proteins MAP2, MAP4 and MAPT TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating