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AMACR Monoclonal Antibody, 100ul NGS Oligos Overexpression of this gene has

SKU: 1102291743

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AMACR Monoclonal Antibody, 100ul NGS Oligos Overexpression of this gene hasThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl CoA and C27 bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult onset sensorimotor neuropathy, pigmentary retinopathy, and

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Description

Overexpression of this gene has been implicated in tumorigenesis

Key genes for eye color and hair color also map to chromosome 19

is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus

The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations

Belongs to the NSE2 family

AMACR Monoclonal Antibody, 100ul NGS Oligos Overexpression of this gene hasThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl CoA and C27 bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult onset sensorimotor neuropathy, pigmentary retinopathy, and

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