N2DL3 Polyclonal Antibody, 50ul Cell Screening and Imaging each encoding distinct isoforms

each encoding distinct isoforms

can vary up to 20-fold between individuals

RFX2 (regulatory factor X2) is a member of the regulatory factor X gene family

A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10

and thus may function as a regulator of Rho signaling pathways

N2DL3 Polyclonal Antibody, 50ul Cell Screening and Imaging each encoding distinct isoformsThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.