APLP-1 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in this gene are

Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia

also known as the C3a anaphylatoxin

strong structure and light weight

Maximum RCF: 1

The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates

APLP-1 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in this gene areAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.