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The triple agonist mechanism provides theoretical advantages over dual agonists like tirzepatide (Mounjaro) for metabolic research

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Furthermore, in mouse models, MF-766 enhances the efficacy of anti-PD-1 therapy by promoting the infiltration of CD8 + T cells, NK cells, and conventional dendritic cells into the tumor microenvironment, shifting macrophage phenotypes toward M1-like ones, and reducing the number of granulocytic MDSCs

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