NR1H4 Polyclonal Antibody, 100ul Dry Bath Mice deficient for this gene

Mice deficient for this gene have increased fat mass despite decreased food intake

The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel| and may play a role in kidney tumorigenesis

MYL3 encodes myosin light chain 3

The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis

PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) is a Protein Coding gene

NR1H4 Polyclonal Antibody, 100ul Dry Bath Mice deficient for this geneThis gene encodes a ligand activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.