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LKB1(Phospho Thr189) Polyclonal Antibody, 50ul Protein Analysis This gene encodes a MAPKKK

SKU: 5050252786

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SEK162.00 SEK206.00

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LKB1(Phospho Thr189) Polyclonal Antibody, 50ul Protein Analysis This gene encodes a MAPKKKThis gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not

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Description

This gene encodes a MAPKKK

Play important roles in coordinating transcription activation and repression by MAFK

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway

but the full-length nature of only one has been determined

DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro

LKB1(Phospho Thr189) Polyclonal Antibody, 50ul Protein Analysis This gene encodes a MAPKKKThis gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not

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