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SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis Translocation t(1

SKU: 47426873307

4.7
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SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis Translocation t(1SNX4 (sorting nexin 4) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may

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Description

Translocation t(1

platelet type 8 (BDPLT8)

The encoded protein (cholinergic receptor nicotinic alpha 3 subunit) is a ligand-gated ion channel that likely plays a role in neurotransmission

When activated| the encoded protein is known to inhibit CDC25C phosphatase| preventing entry into mitosis| and has been shown to stabilize the tumor suppressor protein p53| leading to cell cycle arrest in G1

Naturally occuring read-through transcripts

SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis Translocation t(1SNX4 (sorting nexin 4) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may

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