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292 In HD, the GABAergic neurons in the striatum and cortex are the most affected, contributing to clinical hallmarks such as chorea, cognitive impairment and nonmotor symptoms

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As depicted in Figure 4, unscavenged superoxide inactivates aconitase by displacing Fe +2 from the Fe-S cluster, which then promotes the formation of the damaging hydroxyl radical via reaction with H 2 O 2 and Fenton chemistry

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Inject at the same time daily : Helps your body adapt to a consistent rhythm

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